![Frontiers | Orthotopic and Heterotopic Murine Models of Pancreatic Cancer Exhibit Different Immunological Microenvironments and Different Responses to Immunotherapy Frontiers | Orthotopic and Heterotopic Murine Models of Pancreatic Cancer Exhibit Different Immunological Microenvironments and Different Responses to Immunotherapy](https://www.frontiersin.org/files/Articles/863346/fimmu-13-863346-HTML/image_m/fimmu-13-863346-g001.jpg)
Frontiers | Orthotopic and Heterotopic Murine Models of Pancreatic Cancer Exhibit Different Immunological Microenvironments and Different Responses to Immunotherapy
![A) Schematic of procedure for generating orthotopic glioblastoma mouse... | Download Scientific Diagram A) Schematic of procedure for generating orthotopic glioblastoma mouse... | Download Scientific Diagram](https://www.researchgate.net/publication/282425911/figure/fig2/AS:461350104244225@1487005844766/A-Schematic-of-procedure-for-generating-orthotopic-glioblastoma-mouse-model-B-Weekly.png)
A) Schematic of procedure for generating orthotopic glioblastoma mouse... | Download Scientific Diagram
![Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research - Jonathan P Evans, Boleslaw K Winiarski, Paul A Sutton, Lorenzo Ressel, Carrie A Duckworth, D Mark Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research - Jonathan P Evans, Boleslaw K Winiarski, Paul A Sutton, Lorenzo Ressel, Carrie A Duckworth, D Mark](https://journals.sagepub.com/cms/10.1177/0023677219826165/asset/images/large/10.1177_0023677219826165-fig4.jpeg)
Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research - Jonathan P Evans, Boleslaw K Winiarski, Paul A Sutton, Lorenzo Ressel, Carrie A Duckworth, D Mark
![Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy | Scientific Reports Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-019-47308-z/MediaObjects/41598_2019_47308_Fig1_HTML.png)
Comparative Study of Subcutaneous and Orthotopic Mouse Models of Prostate Cancer: Vascular Perfusion, Vasculature Density, Hypoxic Burden and BB2r-Targeting Efficacy | Scientific Reports
![Frontiers | Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing Frontiers | Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing](https://www.frontiersin.org/files/Articles/690409/fbioe-09-690409-HTML/image_m/fbioe-09-690409-g001.jpg)
Frontiers | Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing
![Characterization of an orthotopic gastric cancer mouse model with lymph node and organ metastases using bioluminescence imaging Corrigendum in /10.3892/ol.2020.11860 Characterization of an orthotopic gastric cancer mouse model with lymph node and organ metastases using bioluminescence imaging Corrigendum in /10.3892/ol.2020.11860](https://www.spandidos-publications.com/article_images/ol/16/4/ol-16-04-5179-g00.jpg)
Characterization of an orthotopic gastric cancer mouse model with lymph node and organ metastases using bioluminescence imaging Corrigendum in /10.3892/ol.2020.11860
![JCI - APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis JCI - APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis](https://dm5migu4zj3pb.cloudfront.net/manuscripts/45000/45008/medium/JCI45008.f1.jpg)
JCI - APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis
![Establishment of image‐guided radiotherapy of orthotopic hepatocellular carcinoma mouse model - Zhou - Animal Models and Experimental Medicine - Wiley Online Library Establishment of image‐guided radiotherapy of orthotopic hepatocellular carcinoma mouse model - Zhou - Animal Models and Experimental Medicine - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/af0c2123-0c27-497c-8564-a8726aef7653/ame212335-fig-0001-m.jpg)
Establishment of image‐guided radiotherapy of orthotopic hepatocellular carcinoma mouse model - Zhou - Animal Models and Experimental Medicine - Wiley Online Library
![MPs | Free Full-Text | Establishment of Orthotopic Liver Tumors by Surgical Intrahepatic Tumor Injection in Mice with Underlying Non-Alcoholic Fatty Liver Disease MPs | Free Full-Text | Establishment of Orthotopic Liver Tumors by Surgical Intrahepatic Tumor Injection in Mice with Underlying Non-Alcoholic Fatty Liver Disease](https://pub.mdpi-res.com/mps/mps-01-00021/article_deploy/html/images/mps-01-00021-g001.png?1570161783)
MPs | Free Full-Text | Establishment of Orthotopic Liver Tumors by Surgical Intrahepatic Tumor Injection in Mice with Underlying Non-Alcoholic Fatty Liver Disease
![IJMS | Free Full-Text | Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure IJMS | Free Full-Text | Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure](https://pub.mdpi-res.com/ijms/ijms-19-02547/article_deploy/html/images/ijms-19-02547-ag-550.jpg?1570412409)
IJMS | Free Full-Text | Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure
![Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models | In Vivo Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models | In Vivo](https://iv.iiarjournals.org/content/invivo/34/5/2303/F1.large.jpg)
Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models | In Vivo
![An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis | Nature Protocols An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis | Nature Protocols](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fnprot.2015.080/MediaObjects/41596_2015_Article_BFnprot2015080_Fig1_HTML.jpg)
An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis | Nature Protocols
![Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum](https://prod-shared-star-protocols.s3.amazonaws.com/protocols/435-Fig5.jpg)
Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum
![Orthotopic Inoculation of Ovarian Cancer Cells into Murine Ovary: A Procedure to Establish an Ovarian Cancer Mouse Model to Study Peritoneal Dissemination of Cells | Protocol Orthotopic Inoculation of Ovarian Cancer Cells into Murine Ovary: A Procedure to Establish an Ovarian Cancer Mouse Model to Study Peritoneal Dissemination of Cells | Protocol](https://cloudfront.jove.com/CDNSource/teasers/20385.jpg)
Orthotopic Inoculation of Ovarian Cancer Cells into Murine Ovary: A Procedure to Establish an Ovarian Cancer Mouse Model to Study Peritoneal Dissemination of Cells | Protocol
![Generation of Orthotopic Xenograft Mouse Model of Prostate Cancer Validated by 11C-Choline PET/CT | Journal of Nuclear Medicine Generation of Orthotopic Xenograft Mouse Model of Prostate Cancer Validated by 11C-Choline PET/CT | Journal of Nuclear Medicine](https://jnm.snmjournals.org/content/jnumed/57/supplement_2/1382/F1.large.jpg)
Generation of Orthotopic Xenograft Mouse Model of Prostate Cancer Validated by 11C-Choline PET/CT | Journal of Nuclear Medicine
![Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma | Journal of Translational Medicine | Full Text Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma | Journal of Translational Medicine | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12967-020-02377-x/MediaObjects/12967_2020_2377_Fig1_HTML.png)